Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      31 kDa
    • Amino acids
      122 to 400
    • Tags
      His-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127667 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with 50µl water.

General Info

  • Alternative names
    • FAPP-2
    • FAPP2
    • hFAPP2
    • MGC3358
    • PH domain-containing family A member 8
    • Phosphatidylinositol-four-phosphate adapter protein 2
    • Phosphoinositide binding specificmember 8
    • Phosphoinositol 4 phosphate adaptor protein 2
    • Phosphoinositol 4-phosphate adapter protein 2
    • PKHA8_HUMAN
    • Pleckstrin homology domain containing A8
    • Pleckstrin homology domain containing family A
    • Pleckstrin homology domain containing family A (Phosphoinositide binding specific) member 8
    • Pleckstrin homology domain-containing family A member 8
    • Plekha8
    • PLEKHA8 protein
    • Serologically defined breast cancer antigen NY-BR-86
    see all
  • Function
    Involved in TGN-to-plasma membrane transport and in the formation of post-Golgi constitutive carriers. May play a role in ensuring the coordination of the budding and the fission reactions.
  • Tissue specificity
    Expressed in kidney cell lines.
  • Sequence similarities
    Contains 1 PH domain.
  • Domain
    Interacts with PIP and ARF via plekstrin homology domain.
  • Cellular localization
    Cytoplasm. Localized to perinuclear structures in the trans-Golgi network.
  • Information by UniProt

References

ab127667 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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