Fascin homolog 1 actin bundling protein (Strongylocentrotus purpuratus)
Fascin, sea urchin, homolog of, 1
Singed (Drosophila) like (sea urchin fascin homolog like)
Singed drosophila homolog like
Singed like (fascin homolog sea urchin)
Singed like (fascin homolog sea urchin) (Drosophila)
Singed like protein
Singed, drosophila, homolog of
FunctionOrganizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.
Sequence similaritiesBelongs to the fascin family.
DomainComposed of four beta-trefoil domains.
Post-translational modificationsPhosphorylation on Ser-39 inhibits the actin-binding ability of fascin.