Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      ab89244 is purified using conventional chromatography techniques.

Specifications

Our Abpromise guarantee covers the use of ab89244 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 90 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0

General Info

  • Alternative names
    • 6-bisphosphatase 1
    • 6-bisphosphate 1-phosphohydrolase 1
    • D fructose 1 6 bisphosphate 1 phosphohydrolase 1
    • D-fructose-1
    • EC 3.1.3.11
    • F16P1_HUMAN
    • FBP
    • FBP 1
    • FBP1
    • FBPase 1
    • Fructose 1 6 bisphosphatase 1
    • Fructose bisphosphatase 1
    • Fructose-1
    • Growth inhibiting protein 17
    • Liver fructose bisphosphatase
    see all
  • Pathway
    Carbohydrate biosynthesis; gluconeogenesis.
  • Involvement in disease
    Defects in FBP1 are the cause of fructose-1,6-bisphosphatase deficiency (FBPD) [MIM:229700]. FBPD is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis (lactacidemia) in newborn infants or young children.
  • Sequence similarities
    Belongs to the FBPase class 1 family.
  • Information by UniProt

Images

  • 15% SDS-PAGE showing ab89244 at approximately 39kDa (3µg).

References

ab89244 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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