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Source Escherichia coli
Amino Acid Sequence
Sequence ab89244 is purified using conventional chromatography techniques. Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Purity > 90
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0
6-bisphosphate 1-phosphohydrolase 1
D fructose 1 6 bisphosphate 1 phosphohydrolase 1
Pathway Carbohydrate biosynthesis; gluconeogenesis.
Involvement in disease Defects in FBP1 are the cause of fructose-1,6-bisphosphatase deficiency (FBPD) [MIM:229700]. FBPD is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis (lactacidemia) in newborn infants or young children.
Sequence similarities Belongs to the FBPase class 1 family.
Information by UniProt
Recombinant Human FBP1 protein images
References for Recombinant Human FBP1 protein (ab89244)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"