Recombinant human Fetuin A protein (ab123466)

Overview

Description

  • NatureRecombinant
  • SourceHEK 293 cells
  • Amino Acid Sequence
    • AccessionP02765
    • SpeciesHuman
    • SequenceAPHGPGLIYR QPNCDDPETE EAALVAIDYI NQNLPWGYKH TLNQIDEVKV WPQQPSGELF EIEIDTLETT CHVLDPTPVA RCSVRQLKEH AVEGDCDFQL LKLDGKFSVV YAKCDSSPDS AEDVRKVCQD CPLLAPLNDT RVVHAAKAAL AAFNAQNNGS NFQLEEISRA QLVPLPPSTY VEFTVSGTDC VAKEATEAAK CNLLAEKQYG FCKATLSEKL GGAEVAVTCT VFQTQPVTSQ PQPEGANEAV PTPVVDPDAP PSPPLGAPGL PPAGSPPDSH VLTVVQPSVG AAAGPVVPPC PGRIRHFKV

Specifications

Our Abpromise guarantee covers the use of ab123466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityBiological Activity: Determined by its ability to inhibit Cathespin V cleavage of a fluorogenic peptide substrate Z-LR-AMC (RLUs). The expected IC50 is = 100nM.
  • Applications

    Functional Studies

    HPLC

    SDS-PAGE

  • Endotoxin level< 0.100 Eu/µg
  • Purity> 98 % SDS-PAGE.
    Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • 59 kDa bone sialic acid containing protein
    • A2HS
    • Aa2 066
    • AHS
    • Ahsg
    • Alpha 2 HS glycoprotein
    • Alpha 2 HS glycoprotein chain A
    • Alpha 2 HS glycoprotein chain B
    • Alpha 2 Z globulin
    • Alpha 2HS glycoprotein
    • Alpha-2-HS-glycoprotein chain B
    • Alpha-2-Z-globulin
    • alpha2 Heremans Schmid glycoprotein
    • Asialofetuin
    • Ba alpha 2 glycoprotein
    • Ba-alpha-2-glycoprotein
    • BSP
    • Countertrypin
    • FETUA
    • FETUA_HUMAN
    • Fetuin A
    • Fetuin, mouse, homolog of
    • Fetuin-A
    • FetuinA
    • Glycoprotein PP63
    • HSGA
    • pp63
    see all
  • FunctionPromotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.
  • Tissue specificitySynthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins.
  • Sequence similaritiesBelongs to the fetuin family.
    Contains 2 cystatin fetuin-A-type domains.
  • Post-translational
    modifications
    Phosphorylation sites are present in the extracelllular medium.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Recombinant human Fetuin A protein (ab123466)

ab123466 has not yet been referenced specifically in any publications.

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