ReconstitutionReconstitute in 50 µl 10 mM Tris, pH 7.6 to a concentration of 1.0 mg/ml.
Acidic fibroblast growth factor
Beta endothelial cell growth factor
Beta-endothelial cell growth factor
Endothelial Cell Growth Factor alpha
Endothelial Cell Growth Factor beta
Fibroblast growth factor 1
Fibroblast Growth Factor 1 Acidic
Heparin binding growth factor 1
Heparin binding growth factor 1 precursor
Heparin-binding growth factor 1
FunctionThe heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro.
Sequence similaritiesBelongs to the heparin-binding growth factors family.
Cellular localizationSecreted. Cytoplasm. Cytoplasm > cell cortex. Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1.