Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human
    • Molecular weight
      25 kDa

Associated products

Specifications

Our Abpromise guarantee covers the use of ab9991 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

  • Endotoxin level
    < 0.100 Eu/µg
  • Form
    Lyophilised
  • Additional notes
    The ED50, as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors, is < 0.5 ng/ml, corresponding to a specific activity of > 1 x 106 units/mg.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 50mM Sodium chloride, 10mM Sodium phosphate, pH 8.0

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • FGF 13
    • FGF 17
    • FGF-17
    • FGF13
    • Fgf17
    • FGF17_HUMAN
    • Fibroblast growth factor 17
    • HH20
    see all
  • Function
    Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for normal brain development.
  • Tissue specificity
    Preferentially expressed in the embryonic brain.
  • Sequence similarities
    Belongs to the heparin-binding growth factors family.
  • Developmental stage
    Detected in embryos at E14.5, but not at E10.5 and E19.5. Preferentially expressed in the neuroepithelia of the isthmus and septum of the embryonic brain at E14.5.
  • Cellular localization
    Secreted.
  • Information by UniProt

Images

  • Standard curve for FGF11 (Analyte: ab9991); dilution range 1pg/ml to 1µg/ml using Capture Antibody ab89270 at 1µg/ml and Detector Antibody ab9990 at 0.5µg/ml.

References

ab9991 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab9991.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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