Additional sequence informationFibroblast Growth Factor -19 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 206 amino acids and having a molecular mass of 23 kDa.
ReconstitutionReconstitute ab73213 in sterile 18MOhm-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Fibroblast growth factor 15
Fibroblast growth factor 19
FunctionInvolved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB.
Tissue specificityExpressed in fetal brain, cartilage, retina, and adult gall bladder.
Sequence similaritiesBelongs to the heparin-binding growth factors family.