The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
FGF21, in the absence of β-Klotho, causes some thymidine uptake by BaF3 cells expressing FGF receptors.
% SDS-PAGE. Greater than 90% by SDS-PAGE gel and HPLC analyses.
Reconstituted FGF-21 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. We recommend to reconstitute it in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, further dilute the reconstituted protein in a buffer (example PBS) containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Fibroblast growth factor 21
FunctionStimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB.
Sequence similaritiesBelongs to the heparin-binding growth factors family.