Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionP49789
    • SpeciesHuman
    • SequenceMSFRFGQHLI KPSVVFLKTE LSFALVNRKP VVPGHVLVCP LRPVERFHDL RPDEVADLFQ TTQRVGTVVE KHFHGTSLTF SMQDGPEAGQ TVKHVHVHVL PRKAGDFHRN DSIYEELQKH DKEDFPASWR SEEEMAAEAA ALRVYFQLEH HHHHH
    • Molecular weight18 kDa including tags
    • Amino acids1 to 147
    • TagsHis tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab95856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Purity> 95 % SDS-PAGE.
    ab95856 is purified using conventional chromatography techniques.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, pH 8.0

General Info

  • Alternative names
    • AP3A hydrolase
    • AP3A hydrolase fragile site 3p14.2
    • AP3Aase
    • Bis 5' adenosyl triphosphatase
    • Bis(5' adenosyl) triphosphatase
    • Diadenosine 5' 5''' P1 P3 triphosphate hydrolase
    • Dinucleosidetriphosphatase
    • FRA 3B
    • FRA3B
    • Fragile histidine triad
    • Fragile histidine triad gene
    • Fragile histidine triad protein
    • Tumor suppressor protein
    see all
  • RelevanceFHIT (fragile histidine triad) cleaves adenosine 5' PPP 5' A to yield AMP and ADP. Alterations and deletions of the FHIT gene are strongly linked to the genesis and establishment of human tumors of the lung, cervix, breast, colon, stomach and pancreas. In normal cells, FHIT may act as a tumor suppressor. FHIT physically associates with ubiquitin conjugating enzyme 9.
  • Cellular localizationCytoplasmic

Recombinant Human FHIT protein images

  • 15% SDS-PAGE showing ab95856 at approximately 17.9kDa (3µg).

References for Recombinant Human FHIT protein (ab95856)

ab95856 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"