This product is an active protein and may elicit a biological response in vivo, handle with caution.
12 kDa FK506-binding protein
12 kDa FKBP
FK506 binding protein 1
FK506 binding protein 12
FK506 binding protein 1A
FK506 binding protein 1A (12kD)
FK506 binding protein 1A 12kDa
FK506 binding protein T cell 12 kD
FK506 binding protein, T cell, 12 kD
FK506 binding protein12
FK506-binding protein 1A
Peptidyl prolyl cis trans isomerase
Peptidyl-prolyl cis-trans isomerase FKBP1A
Protein kinase C inhibitor 2
FunctionMay play a role in modulation of ryanodine receptor isoform-1 (RYR-1), a component of the calcium release channel of skeletal muscle sarcoplasmic reticulum. There are four molecules of FKBP12 per skeletal muscle RYR. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Sequence similaritiesBelongs to the FKBP-type PPIase family. FKBP1 subfamily. Contains 1 PPIase FKBP-type domain.