Recombinant human FKBP14 protein (ab119146)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MALIPEPEVK IEVLQKPFIC HRKTKGGDLM LVHYEGYLEK DGSLFHSTHK HNNGQPIWFT LGILEALKGW DQGLKGMCVG EKRKLIIPPA LGYGKEGKGK IPPESTLIFN IDLLEIRNGP RSHESFQEMD LNDDWKLSKD EVKAYLKKEF EKHGAVVNES HHDALVEDIF DKEDEDKDGF ISAREFTYKH DEL
    • Molecular weight
      24 kDa including tags
    • Amino acids
      20 to 211
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab119146 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Specific activity is > 80 nmoles/min/ug, and is defined as the amount of enzyme that cleaves 1 µmole of suc-AAFP-pNA per minute at 1C in Tris-HCl pH8.0 using chymotrypsin.
  • Applications

    SDS-PAGE

  • Purity
    > 90 % SDS-PAGE.
    ab119146 was purified by proprietary chromatographic techniques.
  • Form
    Liquid
  • Additional notes
    ab119146 should be stored desiccated.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 7.40
    Constituents: 10% Glycerol, 89% PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • 22 kDa FK506 binding protein
    • 22 kDa FK506-binding protein
    • 22 kDa FKBP
    • FK506 binding protein 14
    • FK506 binding protein 14 (22 kDa)
    • FK506-binding protein 14
    • FKB14_HUMAN
    • FKBP 22
    • FKBP-14
    • FKBP-22
    • FKBP14
    • FKBP22
    • FLJ20731
    • Peptidyl prolyl cis trans isomerase
    • Peptidyl-prolyl cis-trans isomerase FKBP14
    • PPIase
    • PPIase FKBP14
    • Rotamase
    see all
  • Function
    PPIases accelerate the folding of proteins during protein synthesis.
  • Involvement in disease
    Ehlers-Danlos syndrome, with progressive kyphoscoliosis, myopathy, and hearing loss
  • Sequence similarities
    Contains 2 EF-hand domains.
    Contains 1 PPIase FKBP-type domain.
  • Cellular localization
    Endoplasmic reticulum lumen.
  • Information by UniProt

References

ab119146 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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