The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Specific activity is > 490 nmoles/min/mg, and is defined as the amount of enzyme that cleaves 1 µmole of suc-AAFP-pNA per minute at 25°C in Tris HCl pH 8.0 using chymotrypsin.
>90% by SDS-PAGE.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00 Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol
This product is an active protein and may elicit a biological response in vivo, handle with caution.
25 kDa FK506-binding protein
25 kDa FKBP
FK506 binding protein 25 T cell
FK506 binding protein 25, T cell, 25-KD
FK506 binding protein 3 (25kD)
FK506-binding protein 3
Peptidyl-prolyl cis-trans isomerase FKBP3
Rapamycin binding protein
Rapamycin-selective 25 kDa immunophilin
FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins.
Belongs to the FKBP-type PPIase family. Contains 1 PPIase FKBP-type domain.