Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIG DKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG EICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIR RTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPI GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSF EKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSAN EKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKE HNERDRRIYANMFKKFAEQDAKEEANKAMGKKTSEGVTNEKGTDSQAMEE EKPEGHV
    • Molecular weight
      76 kDa including tags
    • Amino acids
      1 to 457

Specifications

Our Abpromise guarantee covers the use of ab114430 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

General Info

  • Alternative names
    • 51 kDa FK506 binding protein
    • 51 kDa FK506 binding protein 5
    • 51 kDa FK506-binding protein
    • 51 kDa FKBP
    • 54 kDa progesterone receptor associated immunophilin
    • 54 kDa progesterone receptor-associated immunophilin
    • AIG 6
    • AIG6
    • Androgen regulated protein 6
    • Androgen-regulated protein 6
    • FF1 antigen
    • FK506 binding protein 5
    • FK506-binding protein 5
    • FKBP 5
    • FKBP 51
    • FKBP 54
    • FKBP-5
    • FKBP-51
    • FKBP5
    • FKBP5_HUMAN
    • FKBP54
    • HSP90 binding immunophilin
    • HSP90-binding immunophilin
    • MGC111006
    • OTTHUMP00000016268
    • P54
    • Peptidyl prolyl cis trans isomerase
    • Peptidyl-prolyl cis-trans isomerase FKBP5
    • Peptidylprolyl cis trans isomerase
    • PPIase
    • PPIase FKBP5
    • Ptg 10
    • Ptg10
    • Rotamase
    • T cell FK506 binding protein
    see all
  • Function
    Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP.
  • Tissue specificity
    Widely expressed, enriched in testis compared to other tissues.
  • Sequence similarities
    Contains 2 PPIase FKBP-type domains.
    Contains 3 TPR repeats.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt

Images

  • ab114430 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

References

This product has been referenced in:

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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