The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
>95% by SDS-PAGE . Purified using conventional chromatography techniques.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Information available upon request.
CDNA FLJ36733 fis
Coiled coil domain containing 44
Coiled-coil domain-containing protein 44
Translational activator of cytochrome c oxidase 1
Translational activator of mitochondrially-encoded cytochrome c oxidase I
Acts as a translational activator of mitochondrially-encoded cytochrome c oxidase 1.
Involvement in disease
Defects in TACO1 are a cause of Leigh syndrome (LS) [MIM:256000]. LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency.