Recombinant Human FNDC3A protein (ab161448)

Overview

  • Product name
    Recombinant Human FNDC3A protein
  • Protein length
    Protein fragment

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      DPVIYSLQVMLGKDSEFKQIYKGPDSSFRYSSLQLNCEYRFRVCAIRQCQ DSLGHQDLVGPYSTTVLFISQRTEPPASTNRDTVESTRTRRALSDEQCA
    • Amino acids
      1012 to 1110
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab161448 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Fibronectin type III domain containing protein 3a
    • FNDC3
    • HUGO
    • KIAA0970
  • Relevance
    FNDC3A is a member of a three-gene family in mice. It is expressed in several tissues including testis, and encodes a novel protein composed of a proline-rich amino-terminus, nine fibronectin type-III domains, and a hydrophobic carboxy-terminus. The proline-rich region of each family member contains conserved amino acids that include a PPGY consensus binding site for type I WW domain containing proteins. The hydrophobic carboxy-terminus is similar to that found in 'tail-anchored' proteins, integral membrane proteins that are localized to the cytosolic face of the endoplasmic reticulum. Immunohistochemical staining has shown that FNDC3A localizes to the acrosome of spermatids, as well as to Leydig cells in the mouse testis. FNDC3A may be involved in mediating spermatid-Sertoli adhesion during mouse spermatogenesis and mutation of FNDC3A is the cause of male sterility in sys mice. FNDC3A has also been found to be overexpressed in human odontoblasts.

Images

  • ab161448 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab161448 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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