Overview

  • Product name
    Recombinant Human FNTA protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MAATEGVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEAGEAVASP MDDGFVSLDSPSYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVY DYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSLQKDLHE EMNYITAIIEEQPKNYQVWHHRRVLVEWLRDPSQELEFIADILNQDAKNY HAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQRYFVISNTTGY NDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSKYPNLLNQLL DLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNKALELCEILAKEKDT IRKEYWRYIGRSLQSKHSTENDSPTNVQQ
    • Amino acids
      1 to 379
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab158460 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • CAAX farnesyltransferase alpha subunit
    • CAAX farnesyltransferase subunit alpha
    • EC 2.5.1.58
    • EC 2.5.1.59
    • Farnesyl protein transferase alpha subunit
    • Farnesyltransferase CAAX box alpha
    • Farnesyltransferase, CAAX box, alpha
    • Fnta
    • FNTA_HUMAN
    • FPTA
    • FTase alpha
    • FTase-alpha
    • GGTase I alpha
    • GGTase-I-alpha
    • MGC99680
    • OTTHUMP00000229206
    • OTTHUMP00000229262
    • PGGT1A
    • Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit
    • Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
    • Protein prenyltransferase alpha subunit repeat containing 2
    • PTAR2
    • Ras proteins prenyltransferase alpha
    • Ras proteins prenyltransferase subunit alpha
    • Type I protein geranyl geranyltransferase alpha subunit
    • Type I protein geranyl-geranyltransferase subunit alpha
    see all
  • Function
    Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK.
  • Sequence similarities
    Belongs to the protein prenyltransferase subunit alpha family.
    Contains 5 PFTA repeats.
  • Post-translational
    modifications
    Phosphorylated. Phosphorylation is mediated by MUSK upon AGRIN stimulation and results in the activation of FNTA.
  • Information by UniProt

Images

  • ab158460 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab158460 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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