Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionP55316
    • SpeciesHuman
    • SequenceSPFLSLHHPRASSTLSYNGTTSAYPSHPMPYSSVLTQNSLGNNHSFSTAN GLSVDRLVNGE
    • Molecular weight32 kDa including tags
    • Amino acids164 to 224

Specifications

Our Abpromise guarantee covers the use of ab114230 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • FormLiquid
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • BF-1
    • BF-2
    • BF1
    • BF2
    • Brain factor 1
    • Brain factor 2
    • FHKL
    • FKH2
    • FKHL1
    • FKHL2
    • FKHL3
    • FKHL4
    • Forkhead box protein G1
    • Forkhead box protein G1A
    • Forkhead box protein G1B
    • Forkhead box protein G1C
    • Forkhead like 1
    • Forkhead like 2
    • Forkhead like 3
    • Forkhead like 4
    • Forkhead-related protein FKHL1
    • Forkhead-related protein FKHL2
    • Forkhead-related protein FKHL3
    • FOXG1
    • FOXG1_HUMAN
    • FOXG1A
    • FOXG1B
    • FOXG1C
    • HBF 1
    • HBF G2
    • hBF-2
    • HBF2
    • HFK1
    • HFK2
    • HFK3
    • KHL2
    • Oncogene QIN
    • QIN
    see all
  • FunctionTranscription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.
  • Tissue specificityExpression is restricted to the neurons of the developing telencephalon.
  • Involvement in diseaseDefects in FOXG1 are the cause of congenital variant of Rett syndrome (RTTCV) [MIM:613454]. RTTCV is a severe neurodevelopmental disorder with features of classic Rett syndrome but earlier onset in the first months of life. Clinical features include progressive microcephaly, hypotonia, irresponsiveness and irritability in the neonatal period, mental retardation, psychomotor regression and stereotypical movements.
  • Sequence similaritiesContains 1 fork-head DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt

Recombinant Human FOXG1 protein images

  • 12.5% SDS-PAGE showing ab114230 at approximately 32.24kDa stained with Coomassie Blue.

References for Recombinant Human FOXG1 protein (ab114230)

ab114230 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"