The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. ab17121 was purified by anion-exchange and gel-filtration chromatography techniques.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00 Constituents: 2.4% Urea, 0.32% Tris HCl, 10% Glycerol
Blood group Lewis alpha-4-fucosyltransferase
Fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
May catalyze alpha-1,3 and alpha-1,4 glycosidic linkages involved in the expression of Vim-2, Lewis A, Lewis B, sialyl Lewis X and Lewis X/SSEA-1 antigens. May be involved in blood group Lewis determination; Lewis-positive (Le(+)) individuals have an active enzyme while Lewis-negative (Le(-)) individuals have an inactive enzyme. Also acts on the corresponding 1,4-galactosyl derivative, forming 1,3-L-fucosyl links.
Highly expressed in stomach, colon, small intestine, lung and kidney and to a lesser extent in salivary gland, bladder, uterus and liver.
Protein modification; protein glycosylation.
Belongs to the glycosyltransferase 10 family.
Golgi apparatus > Golgi stack membrane. Membrane-bound form in trans cisternae of Golgi.