The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. ab51298 was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
pH: 7.40 Constituents: PBS, 10% Glycerol
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Colony stimulating factor 3
Colony stimulating factor 3 (granulocyte)
Granulocyte colony stimulating factor
Granulocyte colony-stimulating factor
Macrophage granulocyte inducer 2
FunctionGranulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
Sequence similaritiesBelongs to the IL-6 superfamily.
Post-translational modificationsO-glycan consists of Gal-GalNAc disaccharide which can be modified with up to two sialic acid residues (done in recombinantly expressed G-CSF from CHO cells).