Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab89815 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: 150mM Imidazole
    Constituents: 25% Glycerol, 50mM Sodium phosphate, 300mM Sodium chloride, 2mM DTT, 0.1mM PMSF, pH 7.0

General Info

  • Alternative names
    • Gab 1
    • GAB1
    • GAB1_HUMAN
    • GRB 2 associated binder 1
    • GRB 2 associated binding protein 1
    • GRB2 associated binding protein 1 isoform a
    • GRB2 associated binding protein 1 isoform b
    • GRB2-associated binder 1
    • GRB2-associated-binding protein 1
    • Growth factor receptor bound protein 2-associated protein 1
    see all
  • Function
    Probably involved in EGF and insulin receptor signaling.
  • Sequence similarities
    Belongs to the GAB family.
    Contains 1 PH domain.
  • Post-translational
    modifications
    Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains.
  • Information by UniProt

Images

  • SDS-PAGE showing ab89815 at approximately 108kDa.

References

ab89815 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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