FunctionInvolved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.
Tissue specificityUbiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine.
Sequence similaritiesBelongs to the MAP1 LC3 family.
Post-translational modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.