Recombinant Human GADD45A protein (ab117181)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionP24522
    • SpeciesHuman
    • SequenceMTLEEFSAGE QKTERMDKVG DALEEVLSKA LSQRTITVGV YEAAKLLNVD PDNVVLCLLA ADEDDDRDVA LQIHFTLIQA FCCENDINIL RVSNPGRLAE LLLLETDAGP AASEGAEQPP DLHCVLVTNP HSSQWKDPAL SQLICFCRES RYMDQWVPVI NLPERLEHHH HHH
    • Molecular weight19 kDa including tags
    • Amino acids1 to 165
    • TagsHis tag C-Terminus
    • Additional sequence informationGADD45A produced in E.Coli is a single, non-glycosylated polypeptide chain containing 173 amino acids (1-165 a.a.) and having a molecular mass of 19.4kDa.

Specifications

Our Abpromise guarantee covers the use of ab117181 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 85 % SDS-PAGE.
    ab117181 is purified by proprietary chromatographic techniques. Purity is greater than 85.0% as determined by SDS-PAGE.
  • FormLiquid
  • Additional notesFor long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride

General Info

  • Alternative names
    • DDIT 1
    • DDIT-1
    • DDIT1
    • DNA damage inducible transcript 1
    • DNA damage-inducible transcript 1 protein
    • GA45A_HUMAN
    • GADD45
    • GADD45A
    • Growth arrest and DNA damage inducible 45 alpha
    • Growth arrest and DNA damage inducible alpha
    • Growth arrest and DNA damage-inducible protein GADD45 alpha
    see all
  • FunctionBinds to proliferating cell nuclear antigen. Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
  • Sequence similaritiesBelongs to the GADD45 family.
  • Information by UniProt

References for Recombinant Human GADD45A protein (ab117181)

ab117181 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"