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Source Escherichia coli
Amino Acid Sequence
Sequence MTLEEFSAGE QKTERMDKVG DALEEVLSKA LSQRTITVGV YEAAKLLNVD PDNVVLCLLA ADEDDDRDVA LQIHFTLIQA FCCENDINIL
RVSNPGRLAE LLLLETDAGP AASEGAEQPP DLHCVLVTNP HSSQWKDPAL SQLICFCRES RYMDQWVPVI NLPERLEHHH HHH
Molecular weight 19 kDa including tags
Amino acids 1 to 165
Tags His tag C-Terminus
Additional sequence information GADD45A produced in E.Coli is a single, non-glycosylated polypeptide chain containing 173 amino acids (1-165 a.a.) and having a molecular mass of 19.4kDa. Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Purity > 85
% SDS-PAGE. ab117181 is purified by proprietary chromatographic techniques. Purity is greater than 85.0% as determined by SDS-PAGE.
Additional notes For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Constituents: 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride
Function Binds to proliferating cell nuclear antigen. Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
Sequence similarities Belongs to the GADD45 family.
Information by UniProt
References for Recombinant Human GADD45A protein (ab117181)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"