Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionP51570
    • SpeciesHuman
    • SequenceMGSSHHHHHH SSGLVPRGSH MAALRQPQVA ELLAEARRAF REEFGAEPEL AVSAPGRVNL IGEHTDYNQG LVLPMALELM TVLVGSPRKD GLVSLLTTSE GADEPQRLQF PLPTAQRSLE PGTPRWANYV KGVIQYYPAA PLPGFSAVVV SSVPLGGGLS SSASLEVATY TFLQQLCPDS GTIAARAQVC QQAEHSFAGM PCGIMDQFIS LMGQKGHALL IDCRSLETSL VPLSDPKLAV LITNSNVRHS LASSEYPVRR RQCEEVARAL GKESLREVQL EELEAARDLV SKEGFRRARH VVGEIRRTAQ AAAALRRGDY RAFGRLMVES HRSLRDDYEV SCPELDQLVE AALAVPGVYG SRMTGGGFGG CTVTLLEASA APHAMRHIQE HYGGTATFYL SQAADGAKVL CL
    • Molecular weight44 kDa including tags
    • Amino acids1 to 392
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab116435 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    ab116435 was purified by proprietary chromatographic techniques and filter sterilized.
  • FormLiquid
  • Additional notesab116435 although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Please see notes section.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol

General Info

  • Alternative names
    • EC 2.7.1.6
    • epididymis secretory protein Li 19
    • Galactokinase
    • Galactokinase 1
    • Galactose kinase
    • GALK
    • GALK 1
    • GALK1
    • GALK1_HUMAN
    • GK1
    • GLK
    • GLK1
    • HEL-S-19
    see all
  • FunctionMajor enzyme for galactose metabolism.
  • PathwayCarbohydrate metabolism; galactose metabolism.
  • Involvement in diseaseDefects in GALK1 are the cause of galactosemia II (GALCT2) [MIM:230200]. Galactosemia II is an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of galactitol in the lenses.
  • Sequence similaritiesBelongs to the GHMP kinase family. GalK subfamily.
  • Information by UniProt

References for Recombinant Human GALK1 protein (ab116435)

ab116435 has not yet been referenced specifically in any publications.

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