Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionP17677
    • SpeciesHuman
    • SequenceMLCCMRRTKQVEKNDDDQKIEQDGIKPEDKAHKAATKIQASFRGHITRKK LKGEKKDDVQAAEAEANKKDEAPVADGVEKKGEGTTTAEAAPATGSKPDE PGKAGETPSEEKKGEGDAATEQAAPQAPASSEEKAGSAETESATKASTDN SPSSKAEDAPAKEEPKQADVPAAVTAAAATTPAAEDAAAKATAQPPTETG ESSQAEENIEAVDETKPKESARQDEGKEEEPEADQEHA
    • Molecular weight52 kDa including tags
    • Amino acids1 to 238

Specifications

Our Abpromise guarantee covers the use of ab114188 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • FormLiquid
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Axonal membrane protein GAP 43
    • Axonal membrane protein GAP-43
    • B 50
    • Calmodulin binding protein P 57
    • F1
    • GAP 43
    • GAP43
    • Growth Associated Protein 43
    • Growth-associated protein 43
    • Nerve Growth Related Peptide
    • Nerve growth related peptide GAP43
    • NEUM_HUMAN
    • Neural phosphoprotein B 50
    • Neural phosphoprotein B-50
    • Neuromodulin
    • Neuron growth associated protein 43
    • PP46
    • Protein F1
    • QtrA-11580
    • QtrA-13071
    see all
  • FunctionThis protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons.
  • Sequence similaritiesBelongs to the neuromodulin family.
    Contains 1 IQ domain.
  • Post-translational
    modifications
    Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity.
  • Cellular localizationCell membrane. Cell projection > growth cone membrane. Cell junction > synapse. Cytoplasmic surface of growth cone and synaptic plasma membranes.
  • Information by UniProt

Recombinant Human GAP43 protein images

  • ab114188 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

References for Recombinant Human GAP43 protein (ab114188)

ab114188 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"