For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome
Amino Acid Sequence
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.79% Tris HCl, 0.31% Glutathione
Note: Glutathione is reduced
- EC 220.127.116.11
- Gamma ECS
- Gamma glutamylcysteine synthetase
Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.
Involvement in disease
Defects in GCLC are the cause of hemolytic anemia (HAGGSD) [MIM:230450].
Belongs to the glutamate--cysteine ligase type 3 family.
Information by UniProt
Recombinant Human GCLC protein images
References for Recombinant Human GCLC protein (ab112294)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"