The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C.
Constituents: 0.32% Tris HCl, 0.58% Sodium chloride
ReconstitutionReconstitute with water to desired concentration.
Component of gems 3
DEAD (Asp Glu Ala Asp) box polypeptide 20
DEAD box protein 20
DEAD box protein DP 103
DEAD box protein DP103
DEAD/H (Asp Glu Ala Asp/His) box polypeptide 20
DEAD/H (Asp Glu Ala Asp/His) box polypeptide 20 103kD
DEAD/H BOX 20
Probable ATP dependent RNA helicase DDX20
Probable ATP-dependent RNA helicase ddx20
SMN interacting protein
FunctionThe SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs.
Sequence similaritiesBelongs to the DEAD box helicase family. DDX20 subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain.
Cellular localizationCytoplasm. Nucleus > gem. Localized in subnuclear structures next to coiled bodies, called Gemini of Cajal bodies.