The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activityab68364 is devoid of lactogenic (prolactin receptor mediated) activity characteristic to pituitary GHs.
% SDS-PAGE. ab68364 is purified by proprietary chromatographic techniques.
Additional notesUpon reconstitution and filter sterilization ab68364 can be stored at 4°C for up to 4 weeks. For long term storage and more diluted solutions it is recommended to add a carrier protein (0.1% HSA or BSA).
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
ReconstitutionIt is recommended to reconstitute the lyophilized Placental Growth Hormone in 0.4% NaHCO3 or water adjusted to pH 11, not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Growth hormone 2
Growth hormone B2
Growth hormone variant
Placenta specific growth hormone
Placental specific growth hormone
RelevanceGrowth hormone 2 (GH2) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Mutations in this gene lead to placental growth hormone/lactogen deficiency. The major role of GH2 in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
References for Recombinant human GH2 protein (ab68364)
has not yet been referenced specifically in any publications.
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