The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesBest use within three months from the date of receipt of this protein.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Glucose Transporter 2
Glucose Transporter GLUT2
Glucose transporter type 2
Glucose transporter type 2 liver
Glucose transporter, liver/islet
Solute carrier family 2 (facilitated glucose transporter) member 2
Solute carrier family 2 facilitated glucose transporter member 2
Solute carrier family 2, facilitated glucose transporter member 2
FunctionFacilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.
Tissue specificityLiver, insulin-producing beta cell, small intestine and kidney.
Involvement in diseaseFanconi-Bickel syndrome
Sequence similaritiesBelongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
Post-translational modificationsN-glycosylated; required for stability and retention at the cell surface of pancreatic beta cells.