Recombinant Human Glucose Transporter GLUT2 protein (ab112351)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      NAPQQVIISHYRHVLGVPLDDRKAINNYVINSTDELPTISYSMNPKPTPW AEEETVAAAQLITMLWS
    • Molecular weight
      33 kDa including tags
    • Amino acids
      32 to 98
    • Tags
      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab112351 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Glucose Transporter 2
    • Glucose Transporter GLUT2
    • Glucose transporter type 2
    • Glucose transporter type 2 liver
    • Glucose transporter, liver/islet
    • GLUT-2
    • GLUT2
    • GTR2_HUMAN
    • GTT2
    • liver
    • SLC2A2
    • Solute carrier family 2 (facilitated glucose transporter) member 2
    • Solute carrier family 2 facilitated glucose transporter member 2
    • Solute carrier family 2, facilitated glucose transporter member 2
    see all
  • Function
    Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.
  • Tissue specificity
    Liver, insulin-producing beta cell, small intestine and kidney.
  • Involvement in disease
    Fanconi-Bickel syndrome
  • Sequence similarities
    Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
  • Post-translational
    modifications
    N-glycosylated; required for stability and retention at the cell surface of pancreatic beta cells.
  • Cellular localization
    Membrane.
  • Information by UniProt

Images

  • ab112351 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

References

ab112351 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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