Recombinant Human Glucose Transporter GLUT4 protein (ab114176)

Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionP14672
    • SpeciesHuman
    • SequenceRVPETRGRTFDQISAAFHRTPSLLEQEVKPSTELEYLGPDEND
    • Molecular weight30 kDa including tags
    • Amino acids467 to 509

Specifications

Our Abpromise guarantee covers the use of ab114176 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    ELISA

    Western blot

  • FormLiquid
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Glucose transporter GLUT 4
    • Glucose transporter type 4
    • Glucose transporter type 4 insulin responsive
    • GLUT 4
    • GLUT-4
    • GLUT4
    • GTR4_HUMAN
    • Insulin responsive glucose transporter type 4
    • insulin-responsive
    • kug
    • SLC 2A4
    • SLC2A4
    • solute carrier family 2 (facilitated glucose transporter) member 4
    • Solute carrier family 2 member 4
    • Solute carrier family 2, facilitated glucose transporter member 4
    see all
  • FunctionInsulin-regulated facilitative glucose transporter.
  • Tissue specificitySkeletal and cardiac muscles; brown and white fat.
  • Involvement in diseaseDiabetes mellitus, non-insulin-dependent
  • Sequence similaritiesBelongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
  • Post-translational
    modifications
    Sumoylated.
  • Cellular localizationCell membrane. Endomembrane system. Cytoplasm, perinuclear region. Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized. The dileucine internalization motif is critical for intracellular sequestration.
  • Information by UniProt

Recombinant Human Glucose Transporter GLUT4 protein images

  • ab114176 on a 12.5% SDS-PAGE Stained with Coomassie Blue.

References for Recombinant Human Glucose Transporter GLUT4 protein (ab114176)

ab114176 has not yet been referenced specifically in any publications.

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