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Recombinant Human GMP Synthase protein
Full length protein
Amino Acid Sequence
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 0.02% DTT, 0.32% Tris HCl, 30% Glycerol, 0.58% Sodium chloride
GMP synthase [glutamine hydrolyzing]
Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division.
Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.
Involvement in disease
Note=A chromosomal aberration involving GMPS is found in acute myeloid leukemias. Translocation t(3,11)(q25,q23) with MLL.
Contains 1 glutamine amidotransferase type-1 domain.
Contains 1 GMP-binding domain.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"