Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      LFKPFVESYQIICKYLLSEEEDHFSEEQYLAAVRKFTSQLLDQGTSQCYD VLSSDVQKNALAACVRLGVVEKKKINNNCIFNVNEPATTKLEEMLGCKTP IGKPATAKL
    • Amino acids
      572 to 680
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab160030 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Acyl CoA dihydroxyacetonephosphateacyltransferase
    • Acyl-CoA:dihydroxyacetonephosphateacyltransferase
    • DAP AT
    • DAP-AT
    • DAPAT
    • DHAP AT
    • DHAP-AT
    • DHAPAT
    • Dihydroxyacetone phosphate acyltransferase
    • EC 2.3.1.42
    • Glycerone-phosphate O-acyltransferase
    • Glyceronephosphate O acyltransferase
    • GNPAT
    • GNPAT_HUMAN
    • OTTHUMP00000036147
    see all
  • Pathway
    Membrane lipid metabolism; glycerophospholipid metabolism.
  • Involvement in disease
    Defects in GNPAT are the cause of rhizomelic chondrodysplasia punctata type 2 (RCDP2) [MIM:222765]. RDCP2 is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation.
  • Sequence similarities
    Belongs to the GPAT/DAPAT family.
  • Domain
    The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.
  • Cellular localization
    Peroxisome membrane. Exclusively localized to the lumenal side of the peroxisomal membrane.
  • Information by UniProt

Images

  • ab160030 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab160030 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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