Recombinant Human Grancalcin protein (ab103054)

Overview

  • Product name
    Recombinant Human Grancalcin protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHHSSGLVPRGSHMAYPGYGGGFGNFSIQVPGMQMGQPVPETG PAILLDGYSGPAYSDTYSSAGDSVYTYFSAVAGQDGEVDAEELQRCLTQS GINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNAWKENFMT VDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVA CCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTMAI
    • Molecular weight
      26 kDa including tags
    • Amino acids
      1 to 217
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab103054 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 95 % SDS-PAGE.
    ab103054 was purified using conventional chromatography.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, pH 8.0

General Info

  • Alternative names
    • GCA
    • GCL
  • Relevance
    Grancalcin is a calcium binding protein abundant in neutrophils and macrophages. It belongs to the penta EF hand subfamily of proteins which includes sorcin, calpain, and ALG2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule membrane fusion and degranulation.
  • Cellular localization
    50% cytoplasmic, the remainder being attached to the membranes and granules.

Recombinant Human Grancalcin protein images

  • 15% SDS-PAGE analysis of 3µg ab103054.

References for Recombinant Human Grancalcin protein (ab103054)

ab103054 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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