Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTT GRKLREEERRATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRDASR PHVVKVYSEDGACRSVEVAAGATARHVCEMLVQRAHALSDETWGLVECHP HLALERGLEDHESVVEVQAAWPVGGDSRFVFRKNFAKYELFKSSPHSLFP EKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRGSGRKLWKRFF CFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPTDFG FCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQQAQ SRHLHPSCLGSPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQ AWRKKTNHRLSLPMPASGTSLSAAIHRTQLWFHGRISREESQRLIGQQGL VDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQT RFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL
    • Molecular weight
      85 kDa including tags
    • Amino acids
      1 to 532

Specifications

Our Abpromise guarantee covers the use of ab116903 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • B47
    • Epidermal growth factor receptor GRB 7
    • Epidermal growth factor receptor GRB-7
    • GRB7
    • GRB7 adapter protein
    • GRB7_HUMAN
    • Growth factor receptor bound protein 7
    • Growth factor receptor-bound protein 7
    • OTTHUMP00000164349
    • OTTHUMP00000164350
    • OTTHUMP00000164351
    • OTTHUMP00000164352
    see all
  • Function
    Interacts with the cytoplasmic domain of the epidermal growth factor receptor which is then inhibited. The interaction is mediated by the SH2 domain. Also binds to ERBB2.
  • Sequence similarities
    Belongs to the GRB7/10/14 family.
    Contains 1 PH domain.
    Contains 1 Ras-associating domain.
    Contains 1 SH2 domain.
  • Post-translational
    modifications
    Phosphorylated on tyrosine residues.
  • Information by UniProt

Recombinant Human GRB7 protein images

  • 12.5% SDS-PAGE showing ab116903 at approximately 84.59 kDa stained with Coomassie Blue.

References for Recombinant Human GRB7 protein (ab116903)

ab116903 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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