Overview

  • Product name
    Recombinant human GRK5 protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab60862 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Specific Activity: > 33 nmol/min/mg.
  • Applications

    Functional Studies

    SDS-PAGE

  • Form
    Liquid
  • Additional notes

    ab91092 (Cow Casein full length protein) can be utilized as a substrate for assessing Kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • FLJ39780
    • FP2025
    • G protein coupled receptor kinase 5
    • G protein coupled receptor kinase GRK5
    • G protein-coupled receptor kinase 5
    • G protein-coupled receptor kinase GRK5
    • GPRK5
    • GRK-pan
    • GRK5
    • GRK5_HUMAN
    • Pan-GRK
    see all
  • Function
    Specifically phosphorylates the activated forms of G protein-coupled receptors.
  • Tissue specificity
    Highest levels in heart, placenta, lung > skeletal muscle > brain, liver, pancreas > kidney.
  • Sequence similarities
    Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 protein kinase domain.
    Contains 1 RGS domain.
  • Information by UniProt

Images

  • Sample Kinase Activity Plot.
  • ab60862 on SDS-PAGE, MW ~95 kDa.

References

ab60862 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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