The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. ab73815 is purified by proprietary chromatographic techniques. Purity is greater than 98.0% as determined by RP-HPLC and SDS-PAGE.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
ReconstitutionReconstitute in sterile 18MO-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
C-X-C motif chemokine 3
Chemokine (C X C motif) ligand 3
Chemokine (CXC motif) ligand 3
Cytokine induced neutrophil chemoattractant 2
Dendritic cell inflammatory protein 1
GRO protein gamma
Growth regulated protein gamma
Growth-regulated protein gamma
Macrophage inflammatory protein 2 beta precursor
Macrophage inflammatory protein 2-beta
Melanoma growth stimulatory activity gamma
Small inducible cytokine subfamily B
FunctionLigand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.
Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
Post-translational modificationsN-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.