Recombinant Human GRO gamma protein (ab86929)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MASVVTELRC QCLQTLQGIH LKNIQSVNVR SPGPHCAQTE VIATLKNGKK ACLNPASPMV QKIIEKILNK GSTN

Specifications

Our Abpromise guarantee covers the use of ab86929 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.
    purified by using conventional chromatography techniques. Endotoxin Level: < 1.0 EU per 1 µg of protein (determined by LAL method)
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8

General Info

  • Alternative names
    • C-X-C motif chemokine 3
    • C-X-C motif chemokine ligand 3
    • Chemokine (C X C motif) ligand 3
    • Chemokine (CXC motif) ligand 3
    • Cinc 2
    • CINC 2b
    • Cinc2
    • CINC2b
    • CXCL 3
    • Cxcl3
    • CXCL3_HUMAN
    • Cytokine induced neutrophil chemoattractant 2
    • Dcip1
    • Dendritic cell inflammatory protein 1
    • Gm1960
    • GRO protein gamma
    • GRO-gamma
    • GRO-gamma(1-73)
    • GRO-gamma(5-73)
    • GRO3
    • GRO3 oncogene
    • GROG
    • Growth regulated protein gamma
    • Growth-regulated protein gamma
    • Macrophage inflammatory protein 2 beta precursor
    • Macrophage inflammatory protein 2-beta
    • Melanoma growth stimulatory activity gamma
    • Member 3
    • MGSA gamma
    • MIP 2b
    • MIP2-beta
    • MIP2B
    • SCYB3
    • Small inducible cytokine subfamily B
    see all
  • Function
    Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.
  • Sequence similarities
    Belongs to the intercrine alpha (chemokine CxC) family.
  • Post-translational
    modifications
    N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.
  • Cellular localization
    Secreted.
  • Information by UniProt

Images

  • ab86929 on 15% SDS-PAGE (3µg)

References

ab86929 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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