Recombinant human GRO gamma protein (ab9844)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human
    • Molecular weight
      11 kDa

Associated products

Specifications

Our Abpromise guarantee covers the use of ab9844 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

  • Endotoxin level
    < 0.100 Eu/µg
  • Form
    Lyophilised
  • Additional notes
    The biological activity of this product is determined by its ability to chemoattract CXCR2 transfected 293 cells using a concentration range of 10.0-100.0 ng/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    n/a

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • C-X-C motif chemokine 3
    • C-X-C motif chemokine ligand 3
    • Chemokine (C X C motif) ligand 3
    • Chemokine (CXC motif) ligand 3
    • Cinc 2
    • CINC 2b
    • Cinc2
    • CINC2b
    • CXCL 3
    • Cxcl3
    • CXCL3_HUMAN
    • Cytokine induced neutrophil chemoattractant 2
    • Dcip1
    • Dendritic cell inflammatory protein 1
    • Gm1960
    • GRO protein gamma
    • GRO-gamma
    • GRO-gamma(1-73)
    • GRO-gamma(5-73)
    • GRO3
    • GRO3 oncogene
    • GROG
    • Growth regulated protein gamma
    • Growth-regulated protein gamma
    • Macrophage inflammatory protein 2 beta precursor
    • Macrophage inflammatory protein 2-beta
    • Melanoma growth stimulatory activity gamma
    • Member 3
    • MGSA gamma
    • MIP 2b
    • MIP2-beta
    • MIP2B
    • SCYB3
    • Small inducible cytokine subfamily B
    see all
  • Function
    Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.
  • Sequence similarities
    Belongs to the intercrine alpha (chemokine CxC) family.
  • Post-translational
    modifications
    N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab9844 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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