The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Endotoxin level< 0.100 Eu/µg
Additional notesThe biological activity of this product is determined by its ability to chemoattract CXCR2 transfected 293 cells using a concentration range of 10.0-100.0 ng/ml.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
C-X-C motif chemokine 3
C-X-C motif chemokine ligand 3
Chemokine (C X C motif) ligand 3
Chemokine (CXC motif) ligand 3
Cytokine induced neutrophil chemoattractant 2
Dendritic cell inflammatory protein 1
GRO protein gamma
Growth regulated protein gamma
Growth-regulated protein gamma
Macrophage inflammatory protein 2 beta precursor
Macrophage inflammatory protein 2-beta
Melanoma growth stimulatory activity gamma
Small inducible cytokine subfamily B
FunctionLigand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.
Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
Post-translational modificationsN-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.