Recombinant human GSK3 alpha protein (ab42597)

Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Human
    • Tags
      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab42597 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    700 U/mg. One unit is defined as the amount of enzyme that will phosphorylate 1 nmol of glycogen synthase peptide 2 substrate per minute at pH 7.4 and 30C. Assay buffer: 50 mM HEPES, pH 7.4, 3 mM MgCl2, 3 mM MnCl2, 1 mM DTT, 3uM Na-orthovanadate, 0.1 mM ATP, 20 uM substrate, and 0.1 ug recombinant GSK3 alpha.
  • Applications

    Functional Studies

  • Form
    Liquid
  • Additional notes
    Expressed in a Baculovirus infected Sf9 cell expression system.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, 10mM Glutathione, pH 8.0

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • DKFZp686D0638
    • Glycogen synthase kinase 3 alpha
    • Glycogen synthase kinase-3 alpha
    • GSK 3 alpha
    • GSK 3A
    • GSK-3 alpha
    • Gsk3a
    • GSK3A_HUMAN
    • GSK3alpha
    • Serine/threonine protein kinase GSK3A
    see all
  • Function
    Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN.
  • Sequence similarities
    Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
    Contains 1 protein kinase domain.
  • Information by UniProt

References

ab42597 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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