Recombinant human GSK3 alpha protein (ab42597)

Overview

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab42597 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity700 U/mg. One unit is defined as the amount of enzyme that will phosphorylate 1 nmol of glycogen synthase peptide 2 substrate per minute at pH 7.4 and 30C. Assay buffer: 50 mM HEPES, pH 7.4, 3 mM MgCl2, 3 mM MnCl2, 1 mM DTT, 3uM Na-orthovanadate, 0.1 mM ATP, 20 uM substrate, and 0.1 ug recombinant GSK3 alpha.
  • Applications

    Functional Studies

  • FormLiquid
  • Additional notesExpressed in a Baculovirus infected Sf9 cell expression system.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, 10mM Glutathione, pH 8.0

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • DKFZp686D0638
    • Glycogen synthase kinase 3 alpha
    • Glycogen synthase kinase-3 alpha
    • GSK 3 alpha
    • GSK 3A
    • GSK-3 alpha
    • Gsk3a
    • GSK3A_HUMAN
    • GSK3alpha
    • Serine/threonine protein kinase GSK3A
    see all
  • FunctionImplicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN.
  • Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
    Contains 1 protein kinase domain.
  • Information by UniProt

References for Recombinant human GSK3 alpha protein (ab42597)

ab42597 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab42597.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"