General transcription factor IIF, polypeptide 1, 74kDa
Transcription initiation factor IIF subunit alpha
Transcription initiation factor RAP74
FunctionTFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.
Sequence similaritiesBelongs to the TFIIF alpha subunit family.
Post-translational modificationsPhosphorylated on Ser and other residues by TAF1 and casein kinase II-like kinases.