General transcription factor IIF, polypeptide 2, 30kDa
Transcription initiation factor IIF subunit beta
Transcription initiation factor RAP30
FunctionTFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.
Sequence similaritiesBelongs to the TFIIF beta subunit family.
Post-translational modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.