Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab81892 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    1 unit equals 1 nanogram of purified protein.
  • Applications

    SDS-PAGE

    EMSA

  • Purity
    > 95 % SDS-PAGE.

  • Form
    Liquid
  • Additional notes
    1 unit equals 1 nanogram of purified protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0

General Info

  • Alternative names
    • ATP dependent helicase GTF2F2
    • ATP-dependent helicase GTF2F2
    • BTF4
    • General transcription factor IIF 30 kDa subunit
    • General transcription factor IIF polypeptide 2
    • General transcription factor IIF subunit 2
    • General transcription factor IIF, polypeptide 2, 30kDa
    • Gtf2f2
    • RAP30
    • T2FB_HUMAN
    • TF2F2
    • TFIIF
    • TFIIF beta
    • TFIIF-beta
    • Transcription initiation factor IIF subunit beta
    • Transcription initiation factor RAP30
    see all
  • Function
    TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.
  • Sequence similarities
    Belongs to the TFIIF beta subunit family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Nucleus.
  • Information by UniProt

References

ab81892 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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