Recombinant Human GTF2H2 protein (ab158602)

Overview

  • Product name
    Recombinant Human GTF2H2 protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHH GQVRLGMMRHLYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNP ISQIGIIVTKSKRAEKLTELSGNPRKHITSLKKAVDMTCHGEPSLYNSLS IAMQTLKLVLYIMYN
    • Amino acids
      1 to 165
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab158602 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Basic transcription factor 2 44 kDa subunit
    • BTF2
    • BTF2 p44
    • BTF2-p44
    • BTF2P44
    • General transcription factor IIH
    • General transcription factor IIH polypeptide 2
    • General transcription factor IIH subunit 2
    • General transcription factor IIH, polypeptide 2, 44kDa
    • Gtf2h2
    • MGC102806
    • p44
    • T BTF2P44
    • T-BTF2P44
    • TF2H2_HUMAN
    • TFIIH
    • TFIIH basal transcription factor complex p44 subunit
    see all
  • Function
    Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter.
  • Tissue specificity
    Widely expressed, with higher expression in skeletal muscle.
  • Sequence similarities
    Belongs to the GTF2H2 family.
    Contains 1 VWFA domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt

Images

  • ab158602 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab158602 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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