Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MSRSNRQKEY KCGDLVFAKM KGYPHWPARI DEMPEAAVKS TANKYQVFFF GTHETAFLGP KDLFPYEESK EKFGKPNKRK GFSEGLWEIE NNPTVKASGY
    • Molecular weight
      12 kDa
    • Amino acids
      1 to 100
    • Additional sequence information
      The HDGF Human recombinant protein is a single, non-glycosylated polypeptide chain produced in E. coli, having a molecular weight of 11.5kDa and containing 100 amino acids.

Specifications

Our Abpromise guarantee covers the use of ab116408 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.
    Sterile Filtered clear solution
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 10% Glycerol, 0.32% Tris HCl, 0.02% DTT, 0.03% EDTA

General Info

  • Alternative names
    • FLJ96580
    • HDGF
    • HDGF_HUMAN
    • Hepatoma derived growth factor
    • Hepatoma-derived growth factor
    • High mobility group protein 1 like 2
    • High mobility group protein 1-like 2
    • HMG-1L2
    • HMG1L2
    see all
  • Function
    Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Belongs to the HDGF family.
    Contains 1 PWWP domain.
  • Domain
    The PWWP domain harbors the heparin-binding sites and is responsible for DNA-binding, while the C-terminal region is essentially unstructured.
  • Post-translational
    modifications
    Sumoylated by SUMO1. Sumoylation prevents binding to chromatin.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt

References for Recombinant Human HDGF protein (ab116408)

ab116408 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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