Recombinant Human Heme oxygenase 2 protein (ab93468)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceMSAEVETSEG VDESEKKNSG ALEKENQMRM ADLSELLKEG TKEAHDRAEN TQFVKDFLKG NIKKELFKLA TTALYFTYSA LEEEMERNKD HPAFAPLYFP MELHRKEALT KDMEYFFGEN WEEQVQCPKA AQKYVERIHY IGQNEPELLV AHAYTRYMGD LSGGQVLKKV AQRALKLPST GEGTQFYLFE NVDNAQQFKQ LYRARMNALD LNMKTKERIV EEANKAFEYN MQIFNELDQA GSTLARETLE DGFPVHDGKG DMRK
    • Amino acids1 to 264

Specifications

Our Abpromise guarantee covers the use of ab93468 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 90 % SDS-PAGE.
    ab93468 is purified using conventional chromatography techniques.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris, 1mM DTT, pH 8.0

General Info

  • Alternative names
    • Heme oxygenase (decycling) 2
    • Heme oxygenase (decyclizing) 2
    • Heme oxygenase 2
    • HMOX 2
    • Hmox2
    • HMOX2 protein
    • HMOX2_HUMAN
    • HO 2
    • HO-2
    • HO2
    • OTTHUMP00000159847
    see all
  • FunctionHeme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.
  • Sequence similaritiesBelongs to the heme oxygenase family.
    Contains 2 HRM (heme regulatory motif) repeats.
  • Cellular localizationMicrosome. Endoplasmic reticulum.
  • Information by UniProt

Recombinant Human Heme oxygenase 2 protein images

  • 15% SDS-PAGE analysis of ab93468 (3µg).

References for Recombinant Human Heme oxygenase 2 protein (ab93468)

ab93468 has not yet been referenced specifically in any publications.

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