Recombinant Human Hemoglobin subunit alpha protein (ab158638)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLS HGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFK LLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR
    • Amino acids
      1 to 142
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab158638 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Alpha 1 globin
    • Alpha globin
    • Alpha one globin
    • Alpha-globin
    • HBA_HUMAN
    • HBA1
    • HBA2
    • Hemoglobin alpha 1
    • Hemoglobin alpha 1 chain
    • Hemoglobin alpha 1 globin chain
    • Hemoglobin alpha 2
    • Hemoglobin alpha chain
    • Hemoglobin subunit alpha
    • MGC126895
    • MGC126897
    see all
  • Function
    Involved in oxygen transport from the lung to the various peripheral tissues.
  • Tissue specificity
    Red blood cells.
  • Involvement in disease
    Heinz body anemias
    Alpha-thalassemia
    Alpha(0)-thalassemia is associated with non-immune hydrops fetalis, a generalized edema of the fetus with fluid accumulation in the body cavities due to non-immune causes. Non-immune hydrops fetalis is not a diagnosis in itself but a symptom, a feature of many genetic disorders, and the end-stage of a wide variety of disorders.
    Hemoglobin H disease
  • Sequence similarities
    Belongs to the globin family.
  • Post-translational
    modifications
    The initiator Met is not cleaved in variant Thionville and is acetylated.
  • Information by UniProt

Images

  • ab158638 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab158638 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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