Recombinant Human HePTP / PTPN7 protein (ab124560)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionQ5SXQ0
    • SpeciesHuman
    • SequenceMGSSHHHHHH SSGLVPRGSH MGSHMVQAHG GRSRAQPLTL SLGAAMTQPP PEKTPAKKHV RLQERRGSNV ALMLDVRSLG AVEPICSVNT PREVTLHFLR TAGHPLTRWA LQRQPPSPKQ LEEEFLKIPS NFVSPEDLDI PGHASKDRYK TILPNPQSRV CLGRAQSQED GDYINANYIR GYDGKEKVYI ATQGPMPNTV SDFWEMVWQE EVSLIVMLTQ LREGKEKCVH YWPTEEETYG PFQIRIQDMK ECPEYTVRQL TIQYQEERRS VKHILFSAWP DHQTPESAGP LLRLVAEVEE SPETAAHPGP IVVHCSAGIG RTGCFIATRI GCQQLKARGE VDILGIVCQL RLDRGGMIQT AEQYQFLHHT LALYAGQLPE EPSP
    • Molecular weight43 kDa including tags
    • Amino acids1 to 360
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab124560 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity> 90 % SDS-PAGE.
    Purified by using conventional chromatography.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride

General Info

  • Alternative names
    • BPTP 4
    • BPTP4
    • Dual specificity phosphatase 1
    • Hematopoietic protein tyrosine phosphatase
    • Hematopoietic protein-tyrosine phosphatase
    • HEPTP
    • LC PTP
    • LCPTP
    • LPTP
    • Protein tyrosine phoshatase non receptor type stress induced
    • Protein tyrosine phoshatase nonreceptor type stress induced
    • Protein tyrosine phosphatase LC PTP
    • Protein tyrosine phosphatase non receptor type 7
    • Protein-tyrosine phosphatase LC-PTP
    • PTN7_HUMAN
    • PTPN 7
    • Ptpn7
    • PTPNI
    • Tyrosine protein phosphatase non receptor type 7
    • Tyrosine-protein phosphatase non-receptor type 7
    see all
  • FunctionProtein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction.
  • Tissue specificityExpressed exclusively in thymus and spleen.
  • Sequence similaritiesBelongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • Post-translational
    modifications
    Phosphorylated on serine residues in resting T-cells. Phosphorylation increases upon exposure to stimuli that increase intracellular cAMP levels. Phosphorylation leads to dissociation of bound MAP kinases.
  • Cellular localizationCytoplasm.
  • Information by UniProt

Recombinant Human HePTP / PTPN7 protein images

  • 15% SDS-PAGE (3 µg loaded)

References for Recombinant Human HePTP / PTPN7 protein (ab124560)

ab124560 has not yet been referenced specifically in any publications.

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