Overview

  • Product nameRecombinant Human HIF1AN protein
  • Protein lengthFull length protein

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceMAATAAEAVA SGSGEPREEA GALGPAWDES QLRSYSFPTR PIPRLSQSDP RAEELIENEE PVVLTDTNLV YPALKWDLEY LQENIGNGDF SVYSASTHKF LYYDEKKMAN FQNFKPRSNR EEMKFHEFVE KLQDIQQRGG EERLYLQQTL NDTVGRKIVM DFLGFNWNWI NKQQGKRGWG QLTSNLLLIG MEGNVTPAHY DEQQNFFAQI KGYKRCILFP PDQFECLYPY PVHHPCDRQS QVDFDNPDYE RFPNFQNVVG YETVVGPGDV LYIPMYWWHH IESLLNGGIT ITVNFWYKGA PTPKRIEYPL KAHQKVAIMR NIEKMLGEAL GNPQEVGPLL NTMIKGRYN

Specifications

Our Abpromise guarantee covers the use of ab86916 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 90 % SDS-PAGE.
    ab86916 was purified using conventional chromatography techniques.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20mM Tris HCl, pH 8.0

General Info

  • Alternative names
    • DKFZp762F1811
    • Factor inhibiting HIF-1
    • Factor inhibiting HIF1
    • FIH 1
    • FIH-1
    • FIH1
    • FLJ20615
    • FLJ22027
    • HIF1AN
    • HIF1N_HUMAN
    • Hypoxia inducible factor 1 alpha inhibitor
    • Hypoxia inducible factor 1 alpha subunit inhibitor
    • Hypoxia inducible factor asparagine hydroxylase
    • Hypoxia-inducible factor 1-alpha inhibitor
    • Hypoxia-inducible factor asparagine hydroxylase
    • Peptide aspartate beta dioxygenase
    see all
  • FunctionHydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases.
  • Sequence similaritiesContains 1 JmjC domain.
  • Cellular localizationNucleus.
  • Information by UniProt

Recombinant Human HIF1AN protein images

  • 15% SDS-PAGE analysis of 3µg ab86916

References for Recombinant Human HIF1AN protein (ab86916)

ab86916 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"