Recombinant HIV1 + HIV2 envelope antigen protein (ab43024)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Suitable for: ELISA, WB
Description
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Product name
Recombinant HIV1 + HIV2 envelope antigen protein
See all HIV1 + HIV2 envelope antigen proteins and peptides -
Biological activity
This peptide is immunoreactive with all sera of HIV1, HIV type O and HIV2 infected individuals. -
Purity
> 95 % SDS-PAGE.
S-Sepharose > Ceramic Hydroxyapatite > S-300 > G-25 > Dialysis. -
Expression system
Escherichia coli -
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Additional sequence information
The protein contains the C- terminus of gp120 and most of gp41. The protein is conjugated to a 23 amino acids synthetic peptide derived from pg36 of HIV-2.
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Specifications
Our Abpromise guarantee covers the use of ab43024 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
ELISA
Western blot
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Form
Liquid -
Additional notes
This peptide is immunoreactive with all sera of HIV1, HIV type O and HIV2 infected individuals.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 6.00
Constituents: 0.05% Sodium lauryl sulfate, 1.64% Sodium phosphate
General Info
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Alternative names
- Envelope glycoprotein gp160
- Glycoprotein 120
- Glycoprotein 41
see all -
Relevance
Inhibitors targeting HIV1 viral envelope proteins are used as antiretroviral drugs. The surface protein gp120 attaches the virus to the host lymphoid cell by binding to the primary receptor CD4. This interaction induces a structural rearrangement creating a high affinity binding site for a chemokine coreceptor like CXCR4 and/or CCR5. The transmembrane protein gp41 acts as a class I viral fusion protein.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab43024 has not yet been referenced specifically in any publications.