The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesProtein concentration is above or equal to 0.05 mg/ml.
Best use within three months from the date of receipt of this protein.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.79% Tris HCl, 0.3% Glutathione
Class II histocompatibility antigen M alpha chain
HLA class II histocompatibility antigen DM alpha chain
Major histocompatibility complex class II DM alpha
MHC class II antigen DMA
Really interesting new gene 6 protein
RelevanceHuman Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). This antibody can be used for HLA typing. HLA DM plays a critical role in catalyzing the release of class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides.
Cellular localizationLate endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note: Localizes to late endocytic compartment. Associates with lysosome membranes.
Recombinant Human HLA DM protein images
SDS-PAGE - HLA DM protein (ab116751)
12.5% SDS-PAGE analysis of ab116751 at approximately 54.45kDa, stained with Coomassie Blue.
References for Recombinant Human HLA DM protein (ab116751)
has not yet been referenced specifically in any publications.
Publishing research using ab116751? Please let us know so that we can cite the reference in this datasheet.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"