Recombinant Human HMGCS1 protein (ab114524)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      VFAENMKLREDTYHLVNYIPQGSIDSLFEGTWYLVRVDEKHRRTYARRPT PNDDTLDEGVGLVHSNIATEHIPSPAKKVPRLPATAAEPEAAVISNGEH
    • Molecular weight
      37 kDa including tags
    • Amino acids
      422 to 520

Specifications

Our Abpromise guarantee covers the use of ab114524 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 µg/ul. Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • 3 hydroxy 3 methylglutaryl Coenzyme A synthase 1 (soluble)
    • 3-hydroxy-3-methylglutaryl coenzyme A synthase
    • cytoplasmic
    • EC 2.3.3.10
    • HMCS1_HUMAN
    • HMG CoA synthase
    • HMG-CoA synthase
    • HMGCS
    • HMGCS1
    • Hydroxymethylglutaryl CoA synthase, cytoplasmic
    • Hydroxymethylglutaryl-CoA synthase
    • MGC90332
    see all
  • Function
    This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  • Pathway
    Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 2/3.
  • Sequence similarities
    Belongs to the HMG-CoA synthase family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

Images

  • 12.5% SDS-PAGE showing ab114524 at approximately 36.52kDa stained with Coomassie Blue.

References

ab114524 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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