The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. purified by conventional chromatography techniques.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 20mM Tris HCl, pH 8
Adipose specific phospholipase A2
Adipose specific PLA2
Adipose-specific phospholipase A2
Ca independent phospholipase A1/2
Group XVI phospholipase A1/A2
Group XVI phospholipase A2
H rev 107 protein homolog
H REV107 1
H-rev 107 protein homolog
HRAS like suppressor 1
HRAS like suppressor 3
HRAS-like suppressor 1
HRAS-like suppressor 3
Phospholipase A2 group XVI
Renal carcinoma antigen NY REN 65
Renal carcinoma antigen NY-REN-65
FunctionExhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue (By similarity). N- and O-acylation activity is hardly detectable. Might decrease protein phosphatase 2A (PP2A) activity.
Tissue specificityWidely expressed. low expression, if any, in hematopoietic cells and thymus. In testis, confined to round spermatids. Expressed in normal ovarian epithelial cells. Down-regulated in some ovarian carcinomas and testicular germ cell tumors.
Sequence similaritiesBelongs to the H-rev107 family.