Recombinant Human HRASLS3 protein (ab86922)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MRAPIPEPKP GDLIEIFRPF YRHWAIYVGD GYVVHLAPPS EVAGAGAASV MSALTDKAIV KKELLYDVAG SDKYQVNNKH DDKYSPLPCS KIIQRAEELV GQEVLYKLTS ENCEHFVNEL RYGVARSDQV RDV
    • Amino acids
      1 to 133

Associated products

Specifications

Our Abpromise guarantee covers the use of ab86922 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.
    purified by conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20mM Tris HCl, pH 8

General Info

  • Alternative names
    • Adipose specific phospholipase A2
    • Adipose specific PLA2
    • Adipose-specific phospholipase A2
    • AdPLA
    • Ca independent phospholipase A1/2
    • Group XVI phospholipase A1/A2
    • Group XVI phospholipase A2
    • H rev 107 protein homolog
    • H REV107 1
    • H-rev 107 protein homolog
    • HRAS like suppressor 1
    • HRAS like suppressor 3
    • HRAS-like suppressor 1
    • HRAS-like suppressor 3
    • HREV107
    • HREV107 1
    • HREV107 3
    • HREV107-1
    • HREV107-3
    • HRSL3
    • HRSL3_HUMAN
    • Phospholipase A2 group XVI
    • Pla2g16
    • Renal carcinoma antigen NY REN 65
    • Renal carcinoma antigen NY-REN-65
    see all
  • Function
    Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue (By similarity). N- and O-acylation activity is hardly detectable. Might decrease protein phosphatase 2A (PP2A) activity.
  • Tissue specificity
    Widely expressed. low expression, if any, in hematopoietic cells and thymus. In testis, confined to round spermatids. Expressed in normal ovarian epithelial cells. Down-regulated in some ovarian carcinomas and testicular germ cell tumors.
  • Sequence similarities
    Belongs to the H-rev107 family.
  • Cellular localization
    Cytoplasm. Cytoplasm > perinuclear region. Membrane.
  • Information by UniProt

Images

  • ab86922 on 15% SDS-PAGE (3µg)

References

ab86922 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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